Refractory Lupus Choroidopathy
نویسندگان
چکیده
We report a case of bilateral lupus Choroidopathy and central nervous system (CNS) vasculitis in a 43-year-old female with systemic lupus erythematous. The patient improved systemically on high dose steroids and mycophenolate. Choroiditis flared and escalation of therapy with Rituximab achieved CNS disease control. Choroiditis refractory to systemic therapy improved with micropulse laser therapy. Sequential indocyanine green angiography and enhanced depth imaging of optic coherence tomography allowed monitoring the response to therapy. Systemic lupus erythematous (SLE) is an autoimmune disease characterized by production of Autoantibodies directed against ubiquitous self-antigens. Autoantibodies participate in the formation of immune complexes, which deposit in the walls of small vessels in multiple organs, including the choroid 1the renal glomerulus or joints; causing local inflammation and tissue damage [1].
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